Sunitinib

Sunitinib is used in the treatment of kidney cancer and gastrointestinal stromal tumour.

How Sunitinib works?
Sunitinib is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.
Common side effects of Sunitinib
Nausea, Vomiting, Weakness, Edema (swelling), Rash, Abdominal pain, Discoloration of skin, Fatigue, Fever, Dry skin, Bleeding, High blood pressure, Diarrhea, Constipation, Painful blisters on hands and feet, Stomatitis (Inflammation of the mouth), Hair discoloration, Pain in extremities, Back pain, Headache, Joint pain, Weight loss, Cough, Taste change, Indigestion, Breathlessness
How should I take Sunitinib?
You should take Sunitinib exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Sunitinib, as the chances of side effects may be more.
What should I do if I forget a dose?
If you miss a dose of sunitinib by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
In case of emergency/overdose
In case of overdose, call the poison control helpline. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call a doctor.

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    Sunitinib is a drug that is used to treat gastrointestinal stromal tumours (GISTs), which are tumours that grow in the stomach, intestine (bowel), or oesophagus (tube that connects the throat to the stomach), in people who have had tumours that have not responded to imatinib (Gleevec) or who are unable to take imatinib. Advanced renal cell carcinoma is also treated with sunitinib (RCC, a type of cancer that begins in the cells of the kidneys). Sunitinib is also used to help prevent the recurrence of RCC in persons who have had a kidney removed and have RCC that has not spread. Sunitinib is also used to treat pancreatic neuroendocrine tumours (pNETs) in persons who have tumours that have progressed and cannot be treated with surgery. Sunitinib belongs to the kinase inhibitor class of drugs. It works by preventing the aberrant protein from causing cancer cells to multiply. This may help decrease tumours by halting or slowing the spread of cancer cells.

    PLEASE NOTE:

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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