Palbociclib INN 125 mg

Palbociclib is used to treat a type of advanced breast cancer in adults.

How Palbociclib works?
Palbociclib is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells.
Common side effects of Palbociclib
Fatigue, Hair loss, Rash, Vomiting, Diarrhea, Nausea, Decreased appetite, Infection, Decreased white blood cell count, Stomatitis (Inflammation of the mouth), Anemia (low number of red blood cells), Weakness, Fever
How should I take Palbociclib?
You should take Palbociclib exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Palbociclib, as the chances of side effects may be more.
What should I do if I forget a dose?
If you miss a dose of Palbociclib by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
In case of emergency/overdose
In case of overdose, call the poison control helpline. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call a doctor.

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    Palbociclib is a drug that is used to treat breast cancer. It's also used to treat people with breast cancer that has progressed to other organs (oestrogen receptor-positive, human epidermal growth factor receptor 2-negative). It's used in conjunction with hormonal anticancer treatments.
    Palbociclib is a cancer-fighting drug. Chemical messengers Cyclin dependent kinase 4 and 6 are downstream of signalling pathways that contribute to cell proliferation. This medication stops the cancer cell cycle by inhibiting cyclin dependent kinase 4 and 6. (cell growing process). It also disrupts the cell cycle of oestrogen (hormone) receptor-positive breast cancer cells.


    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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