Obeticholic acid is used in the treatment of Primary biliary cirrhosis.

How Obeticholic acid works
Obeticholic acid stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obeticholic acid inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.
Common side effects of Alectinib
mouth or throat pain, fast, irregular, or pounding heartbeat, rash, dizziness, fainting, swelling of the hands, feet, ankles, or lower legs, joint or muscle pain, constipation
How should I take Obeticholic ?
You should take Obeticholic exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Obeticholic , as the chances of side effects may be more.
What should I do if I forget a dose?
If you miss a dose of Obeticholic by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
In case of emergency/overdose
In case of overdose, call the poison control helpline. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call a doctor.

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    Especially in patients with cirrhosis (liver scarring), Obeticholic acid can cause liver damage that can necessitate liver transplantation or result in death. If you have or have ever had cirrhosis of the liver, tell your doctor. It's possible that your doctor will advise you not to take obeticholic acid. Call your doctor right away if you have any of the following symptoms while taking obeticholic acid: yellowing of the skin or eyes, dark urine, black tarry stools, coughing up or vomiting blood, swelling in and around the stomach area, confusion, slurred speech, anxiety, mood swings, or personality changes. Call your doctor right away if you have any of the following symptoms that are severe or do not go away.


    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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