Neratinib

Neratinib is used alone or with other medicines to treat early-stage HER2-positive breast cancer.

How Neratinib works?
Neratinib is used along with capecitabine (Xeloda) to treat a certain type of advanced hormone receptor-positive breast cancer or breast cancer that has spread to other parts of the body after treatment with at least two other medications.
Common side effects of Neratinib
diarrhea, stomach pain, heartburn, bloating, mouth ulcers, loss of appetite, weight loss, nose bleeding, nail problems or changes, muscle spasms
How should I take Neratinib?
You should take Neratinib exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Neratinib, as the chances of side effects may be more.
What should I do if I forget a dose?
If you miss a dose of Neratinib by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
In case of emergency/overdose
In case of overdose, call the poison control helpline. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call a doctor.

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    After treatment with trastuzumab (Herceptin) and other drugs, neratinib is used to treat a specific form of hormone receptor-positive breast cancer (breast cancer that grows in response to hormones such as oestrogen). Neratinib is used in combination with capecitabine (Xeloda) to treat advanced hormone receptor-positive breast cancer or breast cancer that has progressed to other regions of the body following treatment with at least two prior drugs. Neratinib belongs to the kinase inhibitor class of drugs. It works by preventing cancer cells from multiplying by stopping the action of an aberrant protein. This slows or stops cancer cells from spreading.
    Neratinib is a drug that is used to treat early-stage HER2-positive breast cancer. It can be taken alone or in combination with other drugs. Neratinib is also used to treat advanced or metastatic HER2-positive breast cancer that has progressed to other regions of the body (metastatic).

    PLEASE NOTE:

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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