Ponatinib is used to treat certain types of blood cancer (chronic myelogenous leukemia-CML, acute lymphoblastic leukemia-ALL).

How Ponatinib works?
Ponatinib is a cancer medicine that interferes with the growth of some cancer cells. Ponatinibis used in adults to treat a type of blood cancer called chronic myeloid leukemia (CML), or Philadelphia chromosome positive acute lymphoblastic leukemia (ALL).
Common side effects of Ponatinib
weight gain, numb/tingling skin, pain/numbness/burning feeling in fingers/toes, fainting, fast/slow/irregular/pounding heartbeat, eye pain/swelling/irritation, slow wound healing, sudden severe headache, blurred vision/vision problems
How should I take Ponatinib ?
You should take Ponatinib exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Ponatinib , as the chances of side effects may be more.
What should I do if I forget a dose?
If you miss a dose of Ponatinib by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
In case of emergency/overdose
In case of overdose, call the poison control helpline. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call a doctor.

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    Ponatinib can cause life-threatening blood clots in your legs or lungs, as well as heart attacks and strokes. If you have or have ever had a blood clot in your lungs or legs, high blood pressure, hyperlipidemia (high levels of cholesterol in your blood), a slow, fast, or irregular heartbeat, peripheral vascular disease (narrowing of blood vessels in the feet, legs, or arms causing numbness, pain, or coldness in that part of the body), a heart attack, or heart disease, tell your doctor.
    Call your doctor right away if you have any of the following symptoms: Shortness of breath; dizziness or faintness; sudden disorientation or difficulty speaking or understanding; sudden numbness or weakness of one side of the body's face, arm, or leg, arm, back, neck, or jaw pain; feeling of warmth in the lower leg; or swelling of the feet, ankles, or lower legs.


    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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