Alectinib INN 150 mg

Alectinib is used in the treatment of non-small cell lung cancer.

How Alectinib works?
Alectinib is an anticancer medication. It works by blocking certain receptors found on the cancer cells. These receptors cause the cancer cells to grow and multiply very fast. Hence, blocking them helps to slow or stop tumor growth.
Common side effects of Alectinib
Tiredness, Constipation, Peripheral edema, Muscle pain, Muscle weakness, Decreased red blood cell count
How should I take Alectinib ?
You should take Alectinib exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Alectinib, as the chances of side effects may be more.
What should I do if I forget a dose?
If you miss a dose of Alectinib by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
In case of emergency/overdose
In case of overdose, call the poison control helpline. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call a doctor.

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    Alectinib (Alecensa) is a cancer medicine that is used to treat non-small cell lung cancer (NSCLC) in persons who have an ALK gene mutation. Approximately 5% of persons with NSCLC have this mistake. Alectinib is an orally accessible antineoplastic inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK). Alectinib interacts to ALK kinase, ALK fusion proteins, and the gatekeeper mutation ALKL1196M, which is one of the mechanisms of acquired resistance to small-molecule kinase inhibitors, and inhibits them. The inhibition disrupts ALK-mediated signalling and, as a result, tumour cell proliferation in ALK-overexpressing tumour cells is inhibited. ALK is a member of the insulin receptor superfamily that is involved in nervous system development. ALK gene rearrangements and dysregulation have been linked to a number of cancers.


    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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